![Figure 7: The regulation of growth by GH and IGF1 axis[63] 1-appetite centres in brain affecting calorie intake, 2- signal transduction in hepatocyte, 3 – release of IGF-1 from binding proteins , 4 –IGF-1 expression in growth plate, 5- proliferation of chondrocytes at growth plate](https://www.endotext.org/wp-content/uploads/2015/11/EXT-PIT-ch.5a-fig-7.jpg)
Figure 7: The regulation of growth by GH and IGF1 axis[63]
1-appetite centres in brain affecting calorie intake, 2- signal transduction in hepatocyte, 3 – release of IGF-1 from binding proteins , 4 –IGF-1 expression in growth plate, 5- proliferation of chondrocytes at growth plate