Figure 3. 26-year-old man complaining of visual disturbance had a sella MRI (A): A sella mass 5cm in the maximal diameter with supra, infra and left parasella invasion was noted. Serum PRL levels were above 1000 ng/mL. After one year on cabergoline, 0.5 mg/day, there was no tumor reduction and PRL levels were around 800 ng/mL. He was then submitted to transsphenoidal surgery and radiotherapy. Sella MRI (B) two months after the surgery showed a pituitary mass 3.1 cm in the maximal diameter. Despite chiasmal decompression, visual dysfunction was not reversed and, during his follow-up, anterior pituitary function was lost. Prolactin levels on cabergoline, 1.5 mg/week, were 250 ng/ml. After two more years, sella MRI depicted a lesion 2.9 cm. in the maximal diameter (C). There was a progressive rise of PRL levels despite increased cabergoline doses (0.5 mg/d) and another sella MRI (D), after two years, depicted a lesion of 3.1 cm in the maximal diameter.