Figure 6: The hGR gene has 11 different promoters with specific exon 1 sequences.

The hGR gene has 11 different promoter with specific exon 1 sequences.Alternative exon 1s are shown as yellow arrows and arrowheads. The 5’ flanking region of the hGR gene has proximal and distal promoter regions, which span from ~-37,000 to ~-32,000 and from -5,000 to ~0 upstream of the translation initiation site located in exon 2 (shown as ATG and arrowhead) and contains, 1A1, 1A2, 1A3, and 1I, and 1B, 1C, 1D, 1E, 1F and 1H, respectively. Modified from (32, 33).