ENDOTXTFIG08

Figure 8. Variation in the polyglutamine stretch encoded by the (CAG)nCAA repeat in exon 1. The normal range of this stretch is 9 - 38 glutamine residues, while in the motor neuron disease spinal/bulbar muscular atrophy (also called Kennedy's disease) the (CAG)nCAA repeat in exon 1 is expanded and codes for more than 40 Glutamine residues.

Figure 8. Variation in the polyglutamine stretch encoded by the (CAG)nCAA repeat in exon 1. The normal range of this stretch is 9 – 38 glutamine residues, while in the motor neuron disease spinal/bulbar muscular atrophy (also called Kennedy’s disease) the (CAG)nCAA repeat in exon 1 is expanded and codes for more than 40 Glutamine residues.