etx-adrenal-ch4-fig7

Figure 7: Novel Adrenal Androgens. 3bHSD2, 3b-hydroxysteroid dehydrogenase type 2; 11KA4, 11-ketoandrostenedione; 11KT, 11-ketotestosterone; 11OHA4, 11b-hydroxyandrostenedione; 11OHT, 11b-hydroxytestosterone; 17OH-PREG, 17a-hydroxypregnenolone; 17OH-PROG, 17a-hydroxyprogesterone; A4, androstenedione; AKR1C3, aldo-keto reductase 1C3; CYB5A, cytochrome b5; CYP11A1, cytochrome P450 cholesterol side-chain cleavage; CYP11B1, cytochrome P450 11b-hydroxylase; CYP17A1, cytochrome P450 17a-hydroxylase/17,-20-lyase; DHEA, dehydroepiandrosterone; DHEAS, DHEA sulfate; PREG, pregnenolone; StAR, steroidogenic acute regulatory protein; T, testosterone, SULT2A1, Sulfotransferase Family 2A Member 1; PROG, progesterone; CYP17A2 cytochrome P450 family 17 polypeptide 2; 11βHSD2, 11-β-hydroxysteroid dehydrogenase type 2.