Figure 12. Changes in the number of granulosa cells and volume of follicular fluid in human Graafian follicles throughout the course of folliculogenesis. Note that the dominant follicle at ovulation measures ~25mm in diameter and contains ~50 million granulosa cells and 7 ml of follicular fluid. (McNatty KP: Hormonal correlates of follicular development in the human ovary. Aust J Biol Sci 34:249, 1981. Reproduced with permission from CSIRO Publishing.)