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Table of Contents
Introduction
Pathophysiology & Aetiology
Clinical Features
Biochemical confirmation of Cushing's syndrome
Urinary free cortisol
Low-dose dexamethasone suppression test
Circadian rhythm assessment
Other tests
The Differential Diagnosis of Cushing's syndrome
INVESTIGATING ACTH-independent Cushing's syndrome
Identifying the source in ACTH-dependent Cushing's syndrome
Non-invasive tests
Invasive testing
Imaging
Pituitary
Ectopic tumours
Investigative strategy for THE diagnosis and differential diagnosis of Cushing’s syndrome
TREATMENT OF CUSHING’S SYNDROME
Surgical Management
Radiotherapy
Prognosis
Conclusions