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	INTRODUCTION
	DEFINITIONS
	The menopausal transition
	Menopause
	Premature ovarian failure
	PHYSIOLGIC CHANGES ASSOCIATED WITH AGING AND MENOPAUSE
	The cardiovascular system
	Coagulation
	The Skeletal System
	Bone mineral density testing
	Avoiding bone loss
	Treating osteoporosis
	The Central Nervous System
	The Breast
	The thyroid gland
	The ovary
	The adrenal gland
	HORMONAL TREATMENT OF MENOPAUSAL SYMPTOMS AND DISEASES
	Chemoprevention and therapy of breast cancer with hormonal treatment
	Hormonal Treatment of Osteoporosis and Osteopenia
	COMPARISON OF HORMONAL TREATMENTS BY ORGAN SYSTEM
	Treatment of Vasomotor Symptoms
	Treatment of Vaginal Symptoms
	MHT regimens: continuous combined and cyclic regimens
	CONCLUSION